Reference Text • First Edition

The Cellular Rejuvenation Protocol

A Systems-Level Framework for Biological Age Reversal

Author Mullo Saint
Scope 286 pages, 33 chapters
Version 1.0 (December 2025)
Format PDF, immediate access

This reference text presents the Bio-Energetic Sequencing Model—a systematic framework for treating biological aging as an engineering problem with defined constraints. The core insight: intervention efficacy depends critically on cellular energy state at the time of administration. Aged cells cannot execute multiple repair programs simultaneously.

The text provides complete protocol specifications, including intervention dependency mapping, phase transition criteria, biomarker targets, and completion validation. Designed as a practical reference for those implementing sequenced longevity interventions.

Practitioners

Clinicians designing intervention protocols requiring specific dosing, timing, and monitoring frameworks.

Researchers

Those investigating intervention sequencing, cellular bioenergetics, or protocol optimization.

Advanced Readers

Individuals requiring mechanistic depth beyond general longevity literature.

Protocol Designers

Those developing systematic approaches to biological age intervention.

Part IFoundations — Aging as Engineering Problem
Part IIEnergy Systems — NAD+, Mitochondria, Signaling
Part IIICellular Clearance — Autophagy & Proteostasis
Part IVSenescent Cell Removal — Senolytics & Timing
Part VRegeneration — Stem Cells & Growth Factors
Part VIEpigenetic Maintenance — Stabilization Protocols
Part VIIIntegration — The Complete System
AppendixBiomarker Reference Tables
AppendixDosing Calculators & Schedules
AppendixPhase Transition Criteria

Dependency Mapping: Visual and textual representation of which interventions gate which others. Why rapamycin fails in unprepared tissue. Why senolytics require clearance capacity first.

Completion Criteria: How to determine when each phase is complete. Biomarker thresholds, functional assessments, and the distinction between active intervention and maintenance.

Protocol Specifications: Exact dosing schedules, timing windows, and monitoring frameworks. D+Q cycling, fisetin protocols, rapamycin scheduling—real numbers, not suggestions.

Reference Text — PDF $149

Immediate download • 286 pages • Version 1.0 • Lifetime access to updates

Access Reference Text →

Secure payment via Stripe. Institutional inquiries: [email protected]

Suggested Citation Saint, M. (2025). The Cellular Rejuvenation Protocol: A Systems-Level Framework for Biological Age Reversal (1st ed.). Mullo Saint Research. https://research.mullosaint.com/textbook